Tissue-to-blood transport of radiolabelled immunoglobulin injected into the web spaces of the hands of normal subjects and patients with breast cancer-related lymphoedema.
Identifieur interne : 012906 ( Main/Exploration ); précédent : 012905; suivant : 012907Tissue-to-blood transport of radiolabelled immunoglobulin injected into the web spaces of the hands of normal subjects and patients with breast cancer-related lymphoedema.
Auteurs : S J Pain [Royaume-Uni] ; R W Barber ; J R Ballinger ; C K Solanki ; Peter Mortimer (dermatologue) ; A D Purushotham ; A M PetersSource :
- Journal of vascular research [ 1018-1172 ]
Descripteurs français
- KwdFr :
- Dosage par compétition, Femelle, Humains, Immunoglobuline G (métabolisme), Lymphoedème (imagerie diagnostique), Lymphoedème (métabolisme), Lymphoedème (étiologie), Main, Radio-isotopes de l'indium (pharmacocinétique), Radio-isotopes de l'indium (sang), Répartition dans les tissus, Scintigraphie, Technétium (pharmacocinétique), Technétium (sang), Tumeurs du sein ().
- MESH :
- imagerie diagnostique : Lymphoedème.
- métabolisme : Immunoglobuline G, Lymphoedème.
- pharmacocinétique : Radio-isotopes de l'indium, Technétium.
- sang : Radio-isotopes de l'indium, Technétium.
- étiologie : Lymphoedème.
- Dosage par compétition, Femelle, Humains, Main, Répartition dans les tissus, Scintigraphie, Tumeurs du sein.
English descriptors
- KwdEn :
- Breast Neoplasms (complications), Female, Hand, Humans, Immunoglobulin G (metabolism), Indium Radioisotopes (blood), Indium Radioisotopes (pharmacokinetics), Lymphedema (diagnostic imaging), Lymphedema (etiology), Lymphedema (metabolism), Radioligand Assay, Radionuclide Imaging, Technetium (blood), Technetium (pharmacokinetics), Tissue Distribution.
- MESH :
- chemical , blood : Indium Radioisotopes, Technetium.
- chemical , metabolism : Immunoglobulin G.
- complications : Breast Neoplasms.
- diagnostic imaging : Lymphedema.
- etiology : Lymphedema.
- metabolism : Lymphedema.
- chemical , pharmacokinetics : Indium Radioisotopes, Technetium.
- Female, Hand, Humans, Radioligand Assay, Radionuclide Imaging, Tissue Distribution.
Abstract
The ability to return interstitial protein to central blood is key to the defence against oedema. The aim of this study was to quantify this ability by measuring the rate at which radiolabelled human immunoglobulin (HIgG) accumulated in blood following injection into the subcutis of the hand in normal volunteers and in patients with breast cancer-related lymphoedema (BCRL).
DOI: 10.1159/000077289
PubMed: 15017112
Affiliations:
Links toward previous steps (curation, corpus...)
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- to stream PubMed, to step Curation: 004053
- to stream PubMed, to step Checkpoint: 004053
- to stream Ncbi, to step Merge: 001937
- to stream Ncbi, to step Curation: 001937
- to stream Ncbi, to step Checkpoint: 001937
- to stream Main, to step Merge: 013B22
- to stream Main, to step Curation: 012906
Le document en format XML
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<author><name sortKey="Ballinger, J R" sort="Ballinger, J R" uniqKey="Ballinger J" first="J R" last="Ballinger">J R Ballinger</name>
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<author><name sortKey="Solanki, C K" sort="Solanki, C K" uniqKey="Solanki C" first="C K" last="Solanki">C K Solanki</name>
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<author><name sortKey="Mortimer, P S" sort="Mortimer, P S" uniqKey="Mortimer P" first="P S" last="Mortimer">Peter Mortimer (dermatologue)</name>
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<series><title level="j">Journal of vascular research</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Breast Neoplasms (complications)</term>
<term>Female</term>
<term>Hand</term>
<term>Humans</term>
<term>Immunoglobulin G (metabolism)</term>
<term>Indium Radioisotopes (blood)</term>
<term>Indium Radioisotopes (pharmacokinetics)</term>
<term>Lymphedema (diagnostic imaging)</term>
<term>Lymphedema (etiology)</term>
<term>Lymphedema (metabolism)</term>
<term>Radioligand Assay</term>
<term>Radionuclide Imaging</term>
<term>Technetium (blood)</term>
<term>Technetium (pharmacokinetics)</term>
<term>Tissue Distribution</term>
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<term>Femelle</term>
<term>Humains</term>
<term>Immunoglobuline G (métabolisme)</term>
<term>Lymphoedème (imagerie diagnostique)</term>
<term>Lymphoedème (métabolisme)</term>
<term>Lymphoedème (étiologie)</term>
<term>Main</term>
<term>Radio-isotopes de l'indium (pharmacocinétique)</term>
<term>Radio-isotopes de l'indium (sang)</term>
<term>Répartition dans les tissus</term>
<term>Scintigraphie</term>
<term>Technétium (pharmacocinétique)</term>
<term>Technétium (sang)</term>
<term>Tumeurs du sein ()</term>
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<term>Technetium</term>
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<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Lymphedema</term>
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<keywords scheme="MESH" qualifier="imagerie diagnostique" xml:lang="fr"><term>Lymphoedème</term>
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<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Lymphedema</term>
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<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Immunoglobuline G</term>
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<keywords scheme="MESH" qualifier="pharmacocinétique" xml:lang="fr"><term>Radio-isotopes de l'indium</term>
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<term>Technetium</term>
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<keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Radio-isotopes de l'indium</term>
<term>Technétium</term>
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<term>Radionuclide Imaging</term>
<term>Tissue Distribution</term>
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<term>Humains</term>
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<front><div type="abstract" xml:lang="en">The ability to return interstitial protein to central blood is key to the defence against oedema. The aim of this study was to quantify this ability by measuring the rate at which radiolabelled human immunoglobulin (HIgG) accumulated in blood following injection into the subcutis of the hand in normal volunteers and in patients with breast cancer-related lymphoedema (BCRL).</div>
</front>
</TEI>
<affiliations><list><country><li>Royaume-Uni</li>
</country>
</list>
<tree><noCountry><name sortKey="Ballinger, J R" sort="Ballinger, J R" uniqKey="Ballinger J" first="J R" last="Ballinger">J R Ballinger</name>
<name sortKey="Barber, R W" sort="Barber, R W" uniqKey="Barber R" first="R W" last="Barber">R W Barber</name>
<name sortKey="Mortimer, P S" sort="Mortimer, P S" uniqKey="Mortimer P" first="P S" last="Mortimer">Peter Mortimer (dermatologue)</name>
<name sortKey="Peters, A M" sort="Peters, A M" uniqKey="Peters A" first="A M" last="Peters">A M Peters</name>
<name sortKey="Purushotham, A D" sort="Purushotham, A D" uniqKey="Purushotham A" first="A D" last="Purushotham">A D Purushotham</name>
<name sortKey="Solanki, C K" sort="Solanki, C K" uniqKey="Solanki C" first="C K" last="Solanki">C K Solanki</name>
</noCountry>
<country name="Royaume-Uni"><noRegion><name sortKey="Pain, S J" sort="Pain, S J" uniqKey="Pain S" first="S J" last="Pain">S J Pain</name>
</noRegion>
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